Dr. Robert Naviaux has shared a preliminary summary of the results of the Metabolomics Validation Study, which aims to validate his groundbreaking findings of metabolic features of ME/CFS that he published in 2016. The Open Medicine Foundation is funding the study. Dr. Naviaux reports:
“23 of 30 (77%) of the pathway abnormalities in males and females that were found in the ME/CFS1 study were validated in the ME/CFS2 study, despite large differences in clinical practice, and geography between the two patient cohorts.
Overall, these results add support for the conclusions of the ME/CFS1 study. The syndrome of ME/CFS results from the persistence of a dauer-like metabolic program that produces an energy conservation state mediated by a persistent cell danger response (CDR) to harsh environmental conditions, but at the cost of long-term disability.”
OMF will continue to share updates on this study.
We are writing this article to share some exciting news! On Tuesday, September 26, ME advocates delivered copies of the book, The Puzzle Solver, by Tracie White with Ronald W. Davis, PhD, along with information about ME and Long Covid to Senators on the Hill. The books were donated by an individual living with severe ME/CFS in an effort to raise