Update on the Metabolomics Validation Study by OMF

Dr. Robert Naviaux has shared a preliminary summary of the results of the Metabolomics Validation Studywhich aims to validate his groundbreaking findings of metabolic features of ME/CFS that he published in 2016. The Open Medicine Foundation is funding the study. Dr. Naviaux reports:
“23 of 30 (77%) of the pathway abnormalities in males and females that were found in the ME/CFS1 study were validated in the ME/CFS2 study, despite large differences in clinical practice, and geography between the two patient cohorts.
Overall, these results add support for the conclusions of the ME/CFS1 study. The syndrome of ME/CFS results from the persistence of a dauer-like metabolic program that produces an energy conservation state mediated by a persistent cell danger response (CDR) to harsh environmental conditions, but at the cost of long-term disability.”
OMF will continue to share updates on this study.

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A laptop sitting on a desk. In the background, you can see a cup and saucer, some post-it notes and a folder. On the screen is the Scottish Government's website, with a large title that says 'Scottish Good Practice Statement on Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME-CFS).' A red banner is at the bottom of the photo with white writing which says, '#MEAction Scotland responds to the updated Scottish Good Practice Statement on ME.’ The ME Action Scotland logo is in the top left corner.

#MEAction Scotland responds to the updated Scottish Good Practice Statement

The Scottish Government published the updated Scottish Good Practice Statement (SGPS) on ME-CFS on 28th February 2023.  The decision to update the Scottish Good Practice Statement, originally published in 2010, was a result of the Scottish stakeholder review of the 2021 NICE guideline on ME/CFS, and its recommendations for implementing the guideline in Scotland. The

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